Chapter 20 Nicotine and Addiction

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Nicotine and Addiction: Historical

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"The use of tobacco...conquers men with a certain secret pleasure, so that those who

have once become accustomed thereto can hardly be restrained therefrom."

Francis Bacon, Historia Vital et Mortis, 1622 (Adolescent Medicine, June 1993, p.

305)

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"The fetid and nauseating smoke of tobacco was brought...by English

infidels...pleasure-seekers and sensualists...became addicted, and soon even those

who were not pleasure-seekers began to use it. Many even of the...mighty fell into this

addiction."

Turkish historian Ibrahim Pechevi, 1635 (Newsweek, July 29, 1996, p. 80)

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"It is better to take no snuff at all than a little; for it is certain that he who takes a little

will soon take much, and that is why they call it 'the enchanted herb', for those who take

it are so taken by it that they cannot go without it."

Princess Elizabeth Charlotte of Orleans, about 1710 (Licit and Illicit Drugs, p. 211)

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"For thy sake, tobacco, I would do anything but die."

Charles Lamb, 1820

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In 1828 the chemists Posselt and Reimann of the University of Heidelberg isolated

nicotine as the major pharmacoactive ingredient in tobacco. In 1895, Pinner

established the chemical structure of nicotine as that of

3-(1-methyl-2-pyrrolidinyl)pyridine.

Quote from Cigars, p. 55

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Thursday, July 06, 2000

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